SAN FRANCISCO, Calif. - Randy Johnson is retiring after 22 major league seasons. The Big Unit, an overpowering lefty who last June became the 24th pitcher in big league history to win 300 games, made the expected announcement Tuesday on a conference call. A five-time Cy Young Award winner, the 46-year-old Johnson accomplished just about everything in his remarkable career that a player hopes for in baseball. He owns a World Series ring and co-MVP honors, and was a 10-time All-Star. He threw two no-hitters, including a perfect game, and ranks second on the career strikeout list. The 6-foot-10 Johnson finishes with a career record of 303-166 and 4,875 strikeouts in 4,135 1-3 innings.